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Jen-Leih Wu Selected Research

Bongkrekic Acid

2/2016Giant seaperch iridovirus (GSIV) induces mitochondria-mediated cell death that is suppressed by bongkrekic acid and cycloheximide in a fish cell line.
2/2010Aquatic birnavirus induces necrotic cell death via the mitochondria-mediated caspase pathway.
4/2006Betanodavirus induces phosphatidylserine exposure and loss of mitochondrial membrane potential in secondary necrotic cells, both of which are blocked by bongkrekic acid.

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Jen-Leih Wu Research Topics

Disease

22Infections
01/2022 - 04/2002
10Necrosis
10/2021 - 04/2006
6Carcinogenesis
04/2018 - 01/2007
5Neoplasms (Cancer)
01/2018 - 04/2008
3Inflammation (Inflammations)
03/2021 - 04/2018
3Virus Diseases (Viral Diseases)
10/2014 - 07/2011
3Fibrosis (Cirrhosis)
01/2013 - 01/2008
2Bacterial Infections (Bacterial Infection)
01/2020 - 06/2013
2Cholangiocarcinoma
12/2019 - 12/2012
2Muscular Atrophy (Muscle Atrophy)
01/2013 - 09/2012
2Infertility (Sterility)
10/2010 - 06/2008
2Blister (Bulla)
02/2010 - 04/2006
2Starvation
12/2008 - 09/2003
2Fatty Liver
01/2008 - 03/2006
1Neoplasm Metastasis (Metastasis)
12/2019
1Lymphatic Metastasis
01/2018
1Medulloblastoma
07/2015
1Wounds and Injuries (Trauma)
05/2015
1Wound Infection (Wound Infections)
05/2015
1Peritonitis
05/2015
1Pneumonia (Pneumonitis)
04/2015
1Sepsis (Septicemia)
04/2015
1Porcine Reproductive and Respiratory Syndrome (PRRS)
04/2015
1Disease Resistance
08/2014
1Hemolysis
06/2013
1Urethritis
02/2013
1Uterine Cervicitis (Cervicitis)
02/2013
1Pelvic Inflammatory Disease (Pelvic Inflammatory Diseases)
02/2013
1Vaginitis
02/2013
1Liver Neoplasms (Liver Cancer)
01/2013
1Neuromuscular Diseases (Neuromuscular Disease)
01/2013
1Hyperplasia
01/2013

Drug/Important Bio-Agent (IBA)

8Proteins (Proteins, Gene)FDA Link
01/2017 - 11/2005
6Antimicrobial PeptidesIBA
03/2021 - 12/2011
5Pharmaceutical PreparationsIBA
01/2017 - 01/2013
5PhosphatidylserinesIBA
02/2016 - 04/2006
4CytokinesIBA
01/2021 - 02/2011
4ProgranulinsIBA
04/2018 - 01/2007
4Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
04/2018 - 01/2007
3Annexin A5IBA
01/2022 - 04/2006
3Messenger RNA (mRNA)IBA
01/2017 - 01/2007
3Bongkrekic AcidIBA
02/2016 - 04/2006
3Insulin-Like Growth Factor I (IGF-1)IBA
09/2012 - 01/2007
3Matrix Metalloproteinases (MMPs)IBA
07/2011 - 02/2010
3Small Interfering RNA (siRNA)IBA
02/2011 - 06/2008
2Caspase 9IBA
01/2022 - 02/2010
2ChemokinesIBA
03/2021 - 12/2008
2Caspase 3 (Caspase-3)IBA
02/2020 - 02/2010
2Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA
02/2020 - 12/2019
2Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA
01/2020 - 12/2019
2Peptides (Polypeptides)IBA
04/2018 - 12/2009
2Complement C3 (C3 Complement)IBA
04/2018 - 01/2017
2MicroRNAs (MicroRNA)IBA
01/2017 - 10/2008
2ATP Translocases Mitochondrial ADPIBA
02/2016 - 02/2010
2Transcription Factors (Transcription Factor)IBA
09/2015 - 07/2015
2splenotritin (TP3)IBA
05/2015 - 04/2015
2InterferonsIBA
10/2014 - 02/2008
2MorpholinosIBA
10/2014 - 12/2012
2Antisense RNA (Anti-Sense RNA)IBA
10/2010 - 06/2010
2NitroreductasesIBA
10/2010 - 08/2010
2RNA (Ribonucleic Acid)IBA
09/2010 - 04/2008
2Apoptosis Regulatory ProteinsIBA
04/2008 - 06/2007
2Thioacetamide (Thioacetamid)IBA
01/2008 - 03/2006
2Growth Hormone (Somatotropin)IBA
01/2007 - 09/2003
1Propidium (Propidium Iodide)IBA
01/2022
1Antiviral Agents (Antivirals)IBA
10/2021
1Immunoglobulins (Immunoglobulin)IBA
01/2021
1DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA
02/2020
1Eicosapentaenoic AcidIBA
02/2020
1Caspase 8 (Caspase-8)IBA
02/2020
1Docosahexaenoic AcidsIBA
02/2020
1Fatty Acid DesaturasesIBA
12/2019
1HepcidinsIBA
04/2018
1interleukin-21 (interleukin 21)IBA
04/2018
1Muramidase (Lysozyme)IBA
04/2018
1Interleukin-6 (Interleukin 6)IBA
04/2018
1Interleukin-8 (Interleukin 8)IBA
04/2018
1Interleukin-10 (Interleukin 10)IBA
04/2018
1GRN-41IBA
04/2018
1LigandsIBA
01/2018
1Complement System Proteins (Complement)IBA
01/2017
1Phosphotransferases (Kinase)IBA
04/2016
1Protein Synthesis InhibitorsIBA
02/2016
1Factor VIII (Coagulation Factor VIII)IBA
09/2015
1AMP-Activated Protein KinasesIBA
07/2015
1Carbapenems (Carbapenem Antibiotics)IBA
04/2015
1Tigecycline (Tygacil)FDA Link
04/2015
1ImipenemFDA Link
04/2015
1Ampicillin (Omnipen)FDA LinkGeneric
04/2015
1Anti-Bacterial Agents (Antibiotics)IBA
04/2015
1Interferon Type IIBA
04/2015
1Tretinoin (Retinoic Acid)FDA LinkGeneric
04/2015
1Pattern Recognition ReceptorsIBA
04/2015
1Toll-Like Receptors (Toll-Like Receptor)IBA
04/2015
1Interferon Regulatory Factor-1 (Interferon Regulatory Factor 1)IBA
10/2014
1phosphatidylserine receptorIBA
10/2014
1Explosive Agents (Explosives)IBA
09/2014
1Fish OilsIBA
08/2014
1Adenosine Monophosphate (AMP)IBA
06/2013

Therapy/Procedure

1Heterologous Transplantation (Xenotransplantation)
12/2019